Yftah Tal-Gan: search on Z-Library

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1

Structure–Function Analyses of a Staphylococcus epidermidis Autoinducing Peptide Reveals Motifs Critical for AgrC-type Receptor Modulation

Yang, Tian, Tal-Gan, Yftah, Paharik, Alexandra E., Horswill, Alexander R., Blackwell, Helen E.

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 2.55 MB

english, 2016

2

Structure−Activity Relationships (SARs) of the Competence Stimulating Peptide (CSP) in Streptococcus mutans Reveal Motifs Critical for Membrane Protease SepM Recognition and ComD Receptor Activation

Bikash, Chowdhury Raihan, Hamry, Sally R, Tal-Gan, Yftah

Journal:

ACS Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

3

Nanoporous Superhydrophobic Coatings that Promote the Extended Release of Water-Labile Quorum Sensing Inhibitors and Enable Long-Term Modulation of Quorum Sensing in Staphylococcus aureus

Kratochvil, Michael J, Tal-Gan, Yftah, Yang, Tian, Blackwell, Helen E., Lynn, David M.

Journal:

ACS Biomaterials Science & Engineering

Year:

2015

Language:

english

File:

PDF, 1.80 MB

english, 2015

4

Rational Design of Potent Activators and Inhibitors of the Enterococcus faecalis Fsr Quorum Sensing Circuit

McBrayer, Dominic N, Cameron, Crissey D, Gantman, Brooke K, Tal-Gan, Yftah

Journal:

ACS Chemical Biology

Year:

2018

Language:

english

File:

PDF, 940 KB

english, 2018

5

N-methylation of amino acids in Gelatinase Biosynthesis-Activating Pheromone (GBAP) Identifies Key Site for Stability Enhancement with Retention of the Enterococcus faecalis Fsr Quorum Sensing Circuit Response

McBrayer, Dominic N, Gantman, Brooke K, Tal-Gan, Yftah

Journal:

ACS Infectious Diseases

Year:

2019

File:

PDF, 558 KB

2019

6

An Entirely Solid Phase Peptide Synthesis-Based Strategy for Synthesis of Gelatinase Biosynthesis-Activating Pheromone (GBAP) Analogue Libraries: Investigating the Structure–Activity Relationships of the Enterococcus faecalis Quorum Sensing Signal

McBrayer, Dominic N., Gantman, Brooke K., Cameron, Crissey D., Tal-Gan, Yftah

Journal:

Organic Letters

Year:

2017

Language:

english

File:

PDF, 992 KB

english, 2017

7

Metabolic Stability of Peptidomimetics: N-Methyl and Aza Heptapeptide Analogs of a PKB/Akt Inhibitor

Yftah Tal-Gan, Noam S. Freeman, Shoshana Klein, Alexander Levitzki, Chaim Gilon

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 380 KB

english, 2011

8

Backbone Cyclic Peptide Inhibitors of Protein Kinase B (PKB/Akt)

Tal-Gan, Yftah, Hurevich, Mattan, Klein, Shoshana, Ben-Shimon, Avraham, Rosenthal, David, Hazan, Carina, Shalev, Deborah E., Niv, Masha Y., Levitzki, Alexander, Gilon, Chaim

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.57 MB

english, 2011

9

Structural Characterization of Native Autoinducing Peptides and Abiotic Analogues Reveals Key Features Essential for Activation and Inhibition of an AgrC Quorum Sensing Receptor in Staphylococcus aureus

Tal-Gan, Yftah, Ivancic, Monika, Cornilescu, Gabriel, Cornilescu, Claudia C., Blackwell, Helen E.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 2.82 MB

english, 2013

10

Structural Characterization of Competence Stimulating Peptides (CSPs) Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumoniae

Yang, Yifang, Cornilescu, Gabriel, Tal-Gan, Yftah

Journal:

Year:

2018

Language:

english

File:

PDF, 842 KB

english, 2018

11

Development of a Dominant Negative Competence Stimulating Peptide (dnCSP) that Attenuates Streptococcus pneumoniae Infectivity in a Mouse Model of Acute Pneumonia

Koirala, Bimal, Lin, Jingjun, Lau, Gee W, Tal-Gan, Yftah

Journal:

Year:

2018

Language:

english

File:

PDF, 1.61 MB

english, 2018

12

Exploring the Competence Stimulating Peptide (CSP) N-terminal Requirements for Effective ComD Receptor Activation in Group1 Streptococcus pneumoniae

Yang, Yifang, Tal-Gan, Yftah

Journal:

Bioorganic Chemistry

Year:

2019

Language:

english

File:

PDF, 667 KB

english, 2019

13

Defining the hydrophobic interactions that drive competence stimulating peptide (CSP)-ComD binding in Streptococcus pneumoniae

Koirala, Bimal, Hillman, Robert A, Tiwold, Erin K, Bertucci, Michael A, Tal-Gan, Yftah

Journal:

Beilstein Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 901 KB

english, 2018

14

Biological evaluation of native streptococcal competence stimulating peptides reveals potential crosstalk between Streptococcus mitis and Streptococcus pneumoniae and a new scaffold for the development of S. pneumoniae quorum sensing modulators

Milly, Tahmina Ahmed, Tal-Gan, Yftah

Journal:

RSC Chemical Biology

Year:

2020

File:

PDF, 1.82 MB

2020

15

Novel method for the synthesis of urea backbone cyclic peptides using new Alloc-protected glycine building units

Mattan Hurevich, Yftah Tal-Gan, Shoshana Klein, Yaniv Barda, Alexander Levitzki, Chaim Gilon

Journal:

Journal of Peptide Science

Year:

2010

Language:

english

File:

PDF, 281 KB

english, 2010

16

Surface Coatings that Promote Rapid Release of Peptide-Based AgrC Inhibitors for Attenuation of Quorum Sensing in Staphylococcus aureus

Broderick, Adam H., Stacy, Danielle M., Tal-Gan, Yftah, Kratochvil, Michael J., Blackwell, Helen E., Lynn, David M.

Journal:

Advanced Healthcare Materials

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

17

Synthesis and structure–activity relationship studies of peptidomimetic PKB/Akt inhibitors: The significance of backbone interactions

Yftah Tal-Gan, Noam S. Freeman, Shoshana Klein, Alexander Levitzki, Chaim Gilon

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 903 KB

english, 2010

18

Highly Potent Inhibitors of Quorum Sensing in Staphylococcus aureus Revealed Through a Systematic Synthetic Study of the Group-III Autoinducing Peptide

Tal-Gan, Yftah, Stacy, Danielle M., Foegen, Mary K., Koenig, David W., Blackwell, Helen E.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 3.45 MB

english, 2013

19

N-Methyl and peptoid scans of an autoinducing peptide reveal new structural features required for inhibition and activation of AgrC quorum sensing receptors in Staphylococcus aureus

Tal-Gan, Yftah, Stacy, Danielle M., Blackwell, Helen E.

Journal:

Chemical Communications

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

20

Development and utilization of peptide-based quorum sensing modulators in Gram-positive bacteria

McBrayer, Dominic N., Cameron, Crissey D., Tal-Gan, Yftah

Journal:

Organic & Biomolecular Chemistry

Year:

2020

File:

PDF, 3.43 MB

2020

21

Studying protein–peptide interactions using benzophenone units: A case study of protein kinase B/Akt and its inhibitor PTR6154

Yftah Tal-Gan, Shirly Naveh, Shoshana Klein, Ofra Moshel, Alexander Levitzki, Chaim Gilon

Journal:

Analytical Biochemistry

Year:

2012

Language:

english

File:

PDF, 509 KB

english, 2012

22

Structure Activity Relationship Study of the XIP Quorum Sensing Pheromone in Streptococcus mutans Reveal Inhibitors of the Competence Regulon

Bikash, Chowdhury Raihan, Tal-Gan, Yftah

Journal:

ACS Chemical Biology

Year:

2020

File:

PDF, 712 KB

2020

23

Developing potent backbone cyclic peptides bearing the shared epitope sequence as rheumatoid arthritis drug-leads

Shirly Naveh, Yftah Tal-Gan, Song Ling, Amnon Hoffman, Joseph Holoshitz, Chaim Gilon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 444 KB

english, 2012

24

Characterization of structural elements in native autoinducing peptides and non-native analogues that permit the differential modulation of AgrC-type quorum sensing receptors in Staphylococcus aureus

Tal-Gan, Yftah, Ivancic, Monika, Cornilescu, Gabriel, Blackwell, Helen E.

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 3.30 MB

english, 2015

25

Highly Stable, Amide-Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor in Staphylococcus aureus

Tal-Gan, Yftah, Ivancic, Monika, Cornilescu, Gabriel, Yang, Tian, Blackwell, Helen E.

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

26

Structural Characterization of Competence Stimulating Peptides (CSPs) Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumoniae

Yang, Yifang, Cornilescu, Gabriel, Tal-Gan, Yftah

Journal:

Year:

2018

File:

PDF, 842 KB

2018

27

The importance of amide protons in peptide drug development

Harrington, Anthony, Tal-Gan, Yftah

Journal:

Future Medicinal Chemistry

Year:

2019

File:

PDF, 217 KB

2019

28

Attenuating the Selection of Vancomycin Resistance Among Enterococci Through the Development of Peptide-Based Vancomycin Antagonists

Mull, Ryan W, Brennan, Alec A, Russ, Brittany R, Tal-Gan, Yftah

Journal:

ACS Infectious Diseases

Year:

2020

File:

PDF, 1.31 MB

2020

29

Recent Advances in GLP-1 Receptor Agonists for Use in Diabetes Mellitus

McBrayer, Dominic N., Tal-Gan, Yftah

Journal:

Drug Development Research

Year:

2017

Language:

english

File:

PDF, 154 KB

english, 2017

30

Structure–Activity Relationships of the Competence Stimulating Peptides (CSPs) in Streptococcus pneumoniae Reveal Motifs Critical for Intra-group and Cross-group ComD Receptor Activation

Yang, Yifang, Koirala, Bimal, Sanchez, Lucia A., Phillips, Naiya R., Hamry, Sally R., Tal-Gan, Yftah

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.13 MB

english, 2017

31

Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity in Streptococcus pneumoniae

Yang, Yifang, Lin, Jingjun, Harrington, Anthony, Cornilescu, Gabriel, Lau, Gee W., Tal-Gan, Yftah

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 2.01 MB

2020

32

Simplified AIP-II Peptidomimetics Are Potent Inhibitors of Staphylococcus aureus AgrC Quorum Sensing Receptors

Vasquez, Joseph K., Tal-Gan, Yftah, Cornilescu, Gabriel, Tyler, Kimberly A., Blackwell, Helen E.

Journal:

Year:

2017

Language:

english

File:

PDF, 7.49 MB

english, 2017

33

Chemical Trapping of Vancomycin: A Potential Strategy for Preventing Selection of Vancomycin-Resistant Enterococci

Horwitz, Ehud, Tal-Gan, Yftah, Temper, Violetta, Shapiro, Mervyn, Gilon, Chaim, Hoffman, Amnon

Journal:

Microbial Drug Resistance

Year:

2012

Language:

english

File:

PDF, 216 KB

english, 2012

34

Unveiling the Importance of Amide Protons in CSP:ComD Interactions in Streptococcus pneumoniae

Koirala, Bimal, Phillips, Naiya R., Tal-Gan, Yftah

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

File:

PDF, 1.53 MB

2019

35

Corrigendum to “Inhibition of inositol monophosphatase (IMPase) at the calbindin-D28k binding site: Molecular and behavioural aspects” [Eur. Neuropsychopharmacol. 23 (2013) 1806–1815]

Levi, Itzhak, Eskira, Yael, Eisenstein, Miriam, Gilon, Chaim, Hoffman, Amnon, Tal-Gan, Yftah, Fanous, Joseph, Bersudsky, Yuly, Belmaker, RH, Agam, Galila, Almog, Orna

Journal:

European Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 282 KB

english, 2015

36

Backbone cyclic helix mimetic of chemokine (C–C motif) receptor 2: A rational approach for inhibiting dimerization of G protein-coupled receptors

Hurevich, Mattan, Ratner-Hurevich, Maya, Tal-Gan, Yftah, Shalev, Deborah E., Ben-Sasson, Shlomo Z., Gilon, Chaim

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

37

Highly Stable, Amide-Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor in Staphylococcus aureus

Tal-Gan, Yftah, Ivancic, Monika, Cornilescu, Gabriel, Yang, Tian, Blackwell, Helen E.

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 1.29 MB

english, 2016

38

Identification of Streptococcus gallolyticus subsp. gallolyticus (biotype I) competence stimulating peptide pheromone

Harrington, Anthony, Tal-Gan, Yftah

Journal:

Journal of Bacteriology

Year:

2018

Language:

english

File:

PDF, 2.79 MB

english, 2018

39

Development of Streptococcus pneumoniae Pan Group Quorum Sensing Modulators

Koirala, Bimal, Tal-Gan, Yftah

Journal:

Year:

2019

Language:

english

File:

PDF, 1.32 MB

english, 2019

40

Microwave-Assisted Solid-Phase Aza-peptide Synthesis: Aza Scan of a PKB/Akt Inhibitor Using Aza-arginine and Aza-proline Precursors

Freeman, Noam S., Tal-Gan, Yftah, Klein, Shoshana, Levitzki, Alexander, Gilon, Chaim

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

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